Have also a look into the readme.txt of the patch
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Unzip this patch into your PATCH_HOME staging directory.
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This installer must be executed using a Java Development Kit (JDK).
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Set your PATH to include your <JDK_LOCATION>\bin
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All the processes which are using files from ORACLE_HOME must be stopped before OPatch upgrade.
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Execute java -jar <PATCH_HOME>\6880880\opatch_generic.jar -silent oracle_home=<ORACLE_HOME_LOCATION>
for example:
java -jar C:\TMP\001_p28186730\6880880\opatch_generic.jar -silent oracle_home=C:\iAS_12c